Simultaneous functions with unique process parameter settings

High-throughput bioreactor system designed for parallel microbial or cell cultivations.

Six individually controlled stainless-steel bioreactors, stirred with bottom magnetic stirrers, with a working volume of 0.2 – 1 litres.

Fully automated cleaning-in-place (CIP), in-situ sterilization (SIP), induction, harvest and calibration sequences allow one-person operation.

Ideal for experimental design, parallel comparison studies, and downscaling experiments.   Each bioreactor is fully instrumented: control of temperature, pH, DO, pressure, programmable stirrer and feed pumps, air and oxygen mass-flow controllers. Optional optical density sensors and outlet gas analyzer, 30 fermentations per week with one operator is a typical throughput.

Additional features (software highlights)

“Multi-switch” function enables multi-paralleling, operations in several reactors
Automated calibration procedures simultaneously in all 6 reactors, no need for dismantling
Advanced optical density measurement algorithm eliminates the disturbances by illumination and air bubbles
Sophisticated gravimetric loop back control of the feed pumps provides regulated feed unaffected by pressure changes or pump-tube deformation
Cascade controllers provide advanced and flexible control of DO by stirrer speed, air-flow, pressure and oxygen supplementation
Customized recipe manager provides easy switchover between optimized parameter sets for different microbial processes
Open database and network connectivity allows seamless connection to high-level supervisory system, LIMS and MES.

The automated twin biogas reactor system is an advanced platform for anaerobic digestion research. It is specifically designed for liquid-based media with solid matter content up to 10-15%, offering a wide range of applications. It operates two or more reactors in parallel for simultaneous testing, with precise monitoring of temperature, pressure, and gas volume. Its built-in gas counter enables real-time analysis of gas production, while an optional gas analyzer module provides data on gas composition. Overall, it offers a reliable and efficient solution for biogas production research, with applications in academia and industry.

Product features:

• • • Application: Comparison studies, continuous, semi-continuous or batch operation
  • • Vessel: The standard equipment consists of 2 x 7L to 15L working volume reactors
  • • Stirrer: Powerful stirring for inhomogeneous media provided by top stirrer
  • • Aeration: Strictly anaerobic manual feeding, applicable for anaerobe cultivation
  • • Temperature control: Electrical heating band(s), T=55-78°C
  • • Measurement & Control: Stirrer speed, temperature, pH, antifoam/level, weight, exhaust analysis
  • • Modules: Peristaltic pumps for feeding, adding acid/base or antifoam, integrated gas analyzers/measurement (CH4/CO2/O2/H2), continuous volumetric gas counter
  • • Cleaning: Manual
  • • Sterilization: Autoclavable (optional)
  • • Software: The BioPhantom^© expert biogas control system can handle up to 8 reactors ideal for parallel studies. The software enables various automated functions for example: automated liquid feeding for unattended operation of continuous feeding experiments. Different parameters – temperature, pH, feeding, stirrer - can be set and controlled individually by each reactor.
  • BioPhantom^© Control Software: Monitoring, Control, Process Management, Automation, Data Logging
  • • Configuration: Twin system, with an option to extend with additional units(up to 8)Benchtop biogas reactor, Glass biogas reactor, Scalable biogas reactor system, Multibioreactor, Modular bioreactor, Anaerobic digester

Further features: Benchtop biogas reactor, Glass biogas reactor, Scalable biogas reactor system, Multibioreactor, Modular bioreactor, Anaerobic digester

Stainless steel, in-situ sterilizable bioreactors in 50-1000 L volumes.

Designed for pilot or manufacturing processes of biological products.

Powerful bottom magnetic coupled stirrer, stainless steel frame system with thermo-system, sterile filters and load cells.

Highly advanced regulations for stirrer, level, temperature, DO, pH, redox, pressure, gasflow and feed pumps. Easy integration of 3rd party instruments and equipment. Optional gas mixing station, gas analyzer, turbidity sensor. Several commercial references in Vaccine production, Probiotic starter cultures.

Vessel: Stainless-steel bioreactor vessels, 5–1000 liter working volume. Stainless- steel lid with 12 standard Pg13.5 instrument ports
Control Tower: One control tower for each bioreactor, including all electronic components, 3 peristaltic pumps on the front, utility and instrument connections on the back for easy accessibility and cable/hose management
Stirrer: Hygienic bottom magnetic coupled stirrer - providing safer sterility, Rushton or pitch blade impeller, propeller
Aeration: Applicable for aerobic/anaerobic cultivation, mass flow controlled, sterile filtered, off-gas cooling
Temperature Control: Electrical heating band, cooling finger
Control: Stirrer speed, temperature, feeding rate, pH (by acid/base or CO2), DO (by stirring, gas-flow or feeding), antifoam/level
Measurement: Exhaust gas analysis (O2/CO2), OD measurement
Modules: Mass flow control of gas-mix (air/O2/CO2), Speed controlled peristaltic pumps for feeding, On-off pumps for adding acid/base or antifoam, Balance(s) for feed control
Cleaning: Manual
Sterilization: in-situ sterilizable with steam
Software: BioPhantom© Control Software

For cell or microbial cultivation

Product Features:

• • Vessel: Duran glass or stainless steel bioreactor vessels, 1–3 liter working volume

Stainless steel lid with 12 standard Pg13.5 instrument ports and top stirrer

• • Control tower: One control tower for each bioreactor, including all electronic components, 3 peristaltic pumps on the front, utility and instrument connections on the back for easy accessibility and cable/hose management
• • Stirrer: Hygienic top stirrer (double mechanical seal), Rushton or pitch blade impeller, propeller
• • Aeration: Applicable for aerobic/anaerobic cultivation, mass flow controlled, sterile filtered, off-gas cooling
• • Temperature control: Electrical heating band, cooling finger
• • Control: Stirrer speed, temperature, feeding rate, pH (by acid/base or CO2), DO (by stirring, gas-flow or feeding), antifoam/level,
• • Measurement: Exhaust gas analysis (O2/CO2), OD measurement
• • Modules: Mass flow control of gas-mix (air/O2/CO2), Speed controlled peristaltic pumps for feeding, On-off pumps for adding acid/base or antifoam, Balance(s) for feed control
• • Cleaning: Manual
• • Sterilization: Autoclavable
• • Software: BioPhantom^© Control Software:

Monitoring and control of process parameters (advanced cascade control and sequences)

Process Management: Historical trends, Alarm/event log, Recipes, Batch reports

• • Configuration: Standalone or multiple 2-6 bioreactors (expandable)
• • Options: Integration of 3^rd party instruments, Perfusion device (ATF), OD measurement, Precision feeding control

Our standard Airlift Bioreactors are built with cylindrical Duran glass vessels. The agitation is carried out by the injected air, therefore there is no need for moving parts inside the vessel. This results in a homogenous environment with low shear forces. This technology is advantageous in filamentous fermentation, biological wastewater treatment, production of single-cell proteins, plant and animal cell cultures. Belach Airlift Bioreactor is controlled by the Bio-Phantom© control software enabling the user to have full control over all the measurement instruments and process control equipment.

Product features:

• • • Application: Comparison studies, continuous, semi-continuous or batch operation
  • • Vessel: The standard vessel is 3,5 liters in volume
  • • Agitation: Air circulation, air inlet by mass-flow controller
  • • Temperature control: Electrical heating band
  • • Measurement & Control: Air-flow, temperature, pH, antifoam/level, weight
  • • Modules: Peristaltic pumps for feeding, adding acid/base or antifoam etc.
  • • Cleaning: Manual
  • • Sterilization: Autoclavable
  • • Control System: The BioPhantom© Control Software can handle up to 6 reactors ideal for parallel studies. The software enables various automated functions for example: automated liquid feeding for unattended operation of continuous feeding experiments. Different parameters – temperature, pH, feeding, air-flow – can be set and controlled individually by each reactor.
  • • BioPhantom^© Control Software: The software is available with the full list of features on a desktop PC or a simplified version can be requested in smaller touch screen modules
  • Customizability: The Airlift reactors are highly customizable to the customers' needs, further control and measurement instruments can be added or existing modules can be integrated